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 Over 30 million adults in the U.S. aged 18 to 70 have varicose veins, with women twice as likely as men to develop varicosities. Varicose veins often require treatment for symptoms including leg pain, aching, heaviness, restless legs, cramps, throbbing, fatigue, itchiness, tingling and oedema. These symptoms are frequently the cause of absenteeism from work, disability and decreased quality of life.